Mentally Jacked

Semaglutide Dosage Calculator

Work out the reconstitution and the exact units to draw for any point in a semaglutide titration. Compounded semaglutide arrives as a powder in varying vial strengths, so the units for a given dose differ depending on how you mix it.

Inputs
Draw to
10units
on your U-100, 0.5 ml syringe (50 u max)
Concentration2.5mg/ml
Volume to draw0.100ml
Doses per vial20shots
Instructions
  1. Reconstitute the 5 mg vial with 2 ml bacteriostatic water.
  2. Draw to 10 units on your U-100, 0.5 ml syringe (the red line).
  3. This delivers a dose of 0.25 mg (250 mcg) per injection.
  4. Store the reconstituted vial refrigerated. Do not shake.

Educational tool only. Not medical advice. Always verify doses independently before use.

The standard schedule

Semaglutide is titrated in steps, typically starting at a low weekly dose and increasing every four weeks as tolerated. The weight management and diabetes products follow different schedules and reach different maximum doses, which is a common source of confusion. Build the full dated calendar, including holds for side effects, in the GLP-1 Titration Calculator.

Reconstitution changes your units, not your dose

More bacteriostatic water means a lower concentration and more units for the same dose. Less water means fewer units. Neither changes how much drug you receive. What matters is choosing a mixing volume that puts each dose on a readable syringe mark, particularly since early titration doses are very small. The same math, and the same precision scoring, powers the Peptide Reconstitution Calculator. Comparing options against tirzepatide? See the Tirzepatide Dosage Calculator for the same breakdown on that drug.

FAQ

How do I reconstitute semaglutide?

Add bacteriostatic water slowly down the vial wall and swirl gently until dissolved, never shaking. The volume you add sets the concentration and therefore how many units each dose requires, so decide it before you start.

How many units of semaglutide should I inject?

It depends entirely on your vial strength and how much water you used. Calculate from your specific concentration rather than copying someone else's unit number, which is a common and serious error.

How long does reconstituted semaglutide last?

Refrigerated, it is generally considered usable for several weeks. Keep it cold, protect it from light, and use sterile technique for every draw.

When should I increase my semaglutide dose?

Standard titration increases every four weeks if the current dose is tolerated. If side effects are significant, holding longer at the current dose is reasonable.

What is the maximum semaglutide dose?

It differs by product and indication, with the weight management product reaching a higher maximum than the diabetes product. Many people achieve their goal below the maximum, and there is no requirement to reach it.