Growth hormone peptides live or die on timing. Inject too close to a meal and insulin blunts the pulse by up to half, wasting the dose entirely. This tool takes your actual meal, sleep and training schedule and places each injection in a genuine fasted window, then shows you the resulting 24-hour growth hormone curve.
Fasted: at least 2 hours after your last meal, and wait ~30 minutes after injecting before you eat. Insulin from food, carbs or fats, blunts the pulse by up to half.
Injected together: draw the GHRH analog and GHRP into one syringe and inject as a single subcutaneous shot so both pathways fire on the same pulse.
Educational estimate of timing and relative pulse shape, not a measurement of your GH output and not medical advice. These peptides are not FDA-approved for these uses (tesamorelin is approved only for HIV-associated lipodystrophy). Individual response varies; an IGF-1 blood test is the only way to know where you actually landed.
Food raises insulin, and insulin is growth hormone's direct antagonist. Eating near an injection blunts the pulse substantially. This applies to fat as well as carbohydrate, since free fatty acids also suppress release through somatostatin.
The practical rule is at least two hours after your last meal, and roughly thirty minutes after injecting before you eat. This tool checks your actual meal times and flags any injection that lands inside a fed window, which is exactly the conflict a generic schedule cannot catch.
Your largest natural growth hormone pulse occurs in early slow wave sleep, when somatostatin is at its lowest. Injecting before bed adds to that surge rather than competing with it. If you only inject once a day, this is the window, and the tool prioritises it accordingly.
A GHRH analog such as CJC-1295 without DAC raises the height of the pulse. A GHRP such as ipamorelin initiates the pulse and suppresses somatostatin. They act on the same pituitary cell through different receptors, so together they produce a considerably larger release than either alone.
The DAC version behaves differently. Its multi day half life produces continuously elevated growth hormone rather than pulses, which is less physiological and blunts your own natural rhythm. The tool flags this distinction. Dosing and reconstitution for either version follow the same math as every other peptide, cross-referenced against The Peptide Database.
The ghrelin receptor saturates at roughly one microgram per kilogram of bodyweight. Beyond that point additional micrograms mostly add side effects rather than growth hormone, which is worth knowing before buying larger vials. Confirm your actual exposure with an IGF-1 test read in context using the Bloodwork Analyzer.
Before bed is the single most valuable window, because it amplifies your largest natural growth hormone pulse during early deep sleep. On waking, fasted, is the second. Post training is useful if muscle growth is the priority.
Largely yes. Insulin from food is growth hormone's antagonist and can blunt the pulse by around half. Wait at least two hours after eating, and roughly thirty minutes after injecting before your next meal.
Yes, and they are commonly combined in a single subcutaneous injection so both pathways fire on the same pulse. Their complementary mechanisms are why this pairing is the standard.
Without DAC, the half life is short and the release stays pulsatile, which mirrors natural physiology. With DAC, the half life extends to days and growth hormone is elevated continuously rather than in pulses, which is less physiological and can blunt your own pulsatility.
An IGF-1 blood test. Growth hormone itself is too pulsatile to measure meaningfully from a single draw, whereas IGF-1 is stable and reflects your average exposure. Timing sets the ceiling, but bloodwork tells you where you actually landed.
