Mentally Jacked

BPC-157 & TB-500 Protocol Builder

A torn tendon and an inflamed gut are not the same problem and should not receive the same protocol. This tool routes by injury: which peptide fits, whether it goes local or systemic, oral or injected, loading or maintenance, plus the cycle timeline and exact reconstitution units.

Auto picks both peptides for this injury and phase.
BPC-157 vial
TB-500 vial
Each vial is solved separately on purpose. Same mg does not mean same units, and TB-500 doses are far larger than BPC-157.
Protocol confidence74/ 100 · As high as the evidence allows
Next: Protocol set. These are research peptides on limited human data. Verify third-party-tested source purity and consult a physician.
Protocol
BPC-157 localTB-500 systemic

BPC-157 injected near the injury concentrates it in the damaged tissue. TB-500 runs systemically alongside for whole-body repair signalling.

BPC-157
400mcg / daysplit 200 mcg AM + PM
Subcutaneous near (not into) the injury site — for local tissue concentration
Loading: 400 mcg twice daily for the first ~10 days, then the maintenance dose above.
Draw 8 units per maintenance dose · 16 units per loading dose (U-100 insulin syringe)
TB-500
2.5mg 2\u00D7/wkloading, weeks 1–4
2mg / wkmaintenance, week 5+
Subcutaneous, abdomen or thigh — rotate sites. It works systemically, so do not inject it into the sore joint.
Draw 100 units per loading dose · 80 units per maintenance dose
Note the gap: 8 units of BPC-157 vs 100 units of TB-500. Drawing the same amount from both, the most common stacking error, would badly underdose TB-500.
Cycle map · 6 weeks
BPC-157TB-5000123456
loading maintenancethen 2–4 weeks off before repeating
Full cycle needs
~20.8 mg BPC-157 → 5 \u00D7 5mg vials~24 mg TB-500 → 5 \u00D7 5mg vials
Before you run this
  • Cancer flag: both peptides promote angiogenesis and cell growth. With any active or prior cancer, avoid them or clear it with oncology first.
  • Research chemicals, not FDA-approved (BPC-157 is on the FDA Category 2 list); human safety data is limited.
  • Source only third-party / lab-verified vials. Purity and sterility drive both safety and results.
  • Sterile technique, fresh needles, refrigerate reconstituted vials.
  • Stop and seek review for redness or swelling past 72 h, fever, or any systemic symptom. Do not exceed ~8 weeks without medical supervision.

Educational estimate built from animal data and reported protocols, not medical advice, not a prescription, and not a claim these peptides are proven or approved for these uses in humans. Doses are conservative starting points to discuss with a qualified clinician.

They work differently, and site matters for one of them

BPC-157 is commonly injected subcutaneously near the injured tissue on the theory that local concentration helps, though animal data shows systemic effects regardless of site. For gut conditions the oral route is preferred, since the arginate salt survives stomach acid and makes direct contact with the tissue you are treating.

TB-500 is systemic. It distributes throughout the body no matter where you inject it, which means injecting it into a painful joint achieves nothing beyond irritating the joint. This is the single most common mistake with the compound. Inject into the abdomen or thigh and rotate sites.

Reconstitution is where stacks go wrong

BPC-157 is dosed in micrograms and TB-500 in milligrams, roughly an eightfold to tenfold difference in volume for typical protocols. Two vials both labelled five milligrams therefore require very different draws. Anyone drawing the same units from both is badly underdosing the TB-500. The tool solves each vial separately and flags the gap, using the same backwards-solving approach as the Peptide Reconstitution Calculator.

Be honest about the evidence

Both compounds rest on animal studies and user reports rather than human trials. BPC-157 appears on the FDA's Category 2 bulk substances list. That does not mean they do nothing, but it does mean confidence should be moderate, purity matters enormously, and nobody should present these as established medicine. See both entries, graded honestly, alongside every other compound in The Peptide Database.

One caution deserves emphasis: both promote angiogenesis and cell proliferation. Anyone with an active or prior cancer diagnosis should avoid them or discuss with an oncologist first. If your protocol also includes growth hormone peptides, time the injections using the GH Peptide Pulse Optimiser to avoid conflicting with meals or sleep.

FAQ

What is the correct BPC-157 dosage?

Commonly around 250 to 500 micrograms daily, scaled loosely to bodyweight, often split into two doses because the half life is short. Loading protocols use higher doses for the first week to ten days before dropping to maintenance.

Where should I inject BPC-157?

For musculoskeletal injuries, subcutaneously near the injured area, not into the joint or tendon itself. For gut issues, the oral arginate form is preferred. For general or systemic use, subcutaneously into the abdomen.

Does TB-500 need to be injected near the injury?

No. TB-500 works systemically and distributes throughout the body regardless of injection site. Injecting it into a sore joint is a common and pointless mistake. Use the abdomen or thigh and rotate sites.

How long should a BPC-157 cycle last?

Typically four to eight weeks, extending to around twelve for gut protocols, followed by time off. Neither compound is hormonal, so no taper is physiologically necessary.

Can you take BPC-157 and TB-500 together?

They are frequently combined, with BPC-157 dosed daily and TB-500 dosed twice weekly during a loading phase then reduced. Just make sure each vial is reconstituted and calculated separately, since their dose scales differ by roughly an order of magnitude.